LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemNexera QX Multiplex LC-MSLCMS-2020 Single Quadrupole Mass SpectrometerLCMS-8045RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8050RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-9030 Quadrupole Time-of-Flight Mass Spectrometer
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Catalog NumberNexera QXLCMS-2020LCMS-8050RX
Price
Ionization Method(s)ESI, APCI, Dual IonizationESI, APCI, Dual IonizationESI, APCIESI, APCI, Dual Ionization, Micro-ESIESI, APCI
Mass AnalyzerQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsSingle QuadrupoleTriple QuadrupoleQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQuadrupole Time-of-Flight (Q-TOF)
Scanning SpeedInquire15,000 u/secUp to 15,000 Da/s30,000 u/sec100 Hz maximum acquisition rate
ResolutionInquireR = 2 M0.1 Da (unit resolution)R < 0.7 u FWHM30,000 FWHM
DescriptionThe Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.

  • Multiple stream technology eliminates waiting for column equilibration and system
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Utilizing patented ultrafast (UF) technology, the LCMS-2020 mass spectrometer offers fast measurements and outstanding detection sensitivity for quicker and more accurate detection of trace impurities in a variety of applications.

Features
  • Ultrafast scanning speed of 15,000 u/sec, without
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InquireIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050RX offers outstanding measurement speeds and quantitative performance.
Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated
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Q-TOF mass spectrometer integrating fast quadrupole technology with unique TOF architecture. Features UFaccumulation, UFgrating, UF-FlightTube with temperature control, and iRefTOF technologies for superior sensitivity, mass accuracy, and speed.
QuantityEAEAInquireEAInquire
TypeInquireInquireTriple Quadrupole LC-MS/MSInquireQuadrupole Time-of-Flight (Q-TOF) LC-MS/MS
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