LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemLCMS-8060RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-2050 Mass SpectrometerLCMS-8050RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-9030 Quadrupole Time-of-Flight Mass SpectrometerNexera QX Multiplex LC-MS
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Catalog NumberLCMS-8060RXLCMS-2050LCMS-8050RXNexera QX
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Ionization Method(s)ESI, APCI, Dual Ionization, Micro-ESIESI, APCI, Dual IonizationESI, APCI, Dual Ionization, Micro-ESIESI, APCIESI, APCI, Dual Ionization
Mass AnalyzerQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsSingle QuadrupoleQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQuadrupole Time-of-Flight (Q-TOF)Q1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rods
Scanning SpeedMax. 30,000 u/sec (in all scan modes) (0.1 u step: 300,000 data points/sec)15,000 u/sec30,000 u/sec100 Hz maximum acquisition rateInquire
ResolutionR < 0.7 u FWHM and adjustable to 0.5 uInquireR < 0.7 u FWHM30,000 FWHMInquire
DescriptionThe triple quad LCMS-8060RX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity.
A heat-assisted electrospray ionization probe delivers a highly efficient desolvation process that promotes the ionization of a wide range of target compounds
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The LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy-to-use high-level performance and compactness. To make it accessible to all users, the system is enhanced with technology and ... Read MoreIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050RX offers outstanding measurement speeds and quantitative performance.
Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated
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Q-TOF mass spectrometer integrating fast quadrupole technology with unique TOF architecture. Features UFaccumulation, UFgrating, UF-FlightTube with temperature control, and iRefTOF technologies for superior sensitivity, mass accuracy, and speed.The Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.

  • Multiple stream technology eliminates waiting for column equilibration and system
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QuantityEAEAEAInquireEA
TypeTriple Quad LC-MS/MSInquireInquireQuadrupole Time-of-Flight (Q-TOF) LC-MS/MSInquire
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