LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemOrbitrap IQ-X™ Tribrid™ Mass SpectrometerOrbitrap Eclipse™ Tribrid™ Mass SpectrometerOrbitrap Exploris™ 240 Mass SpectrometerOrbitrap Fusion™ Lumos™ Tribrid™ Mass SpectrometerTox Explorer™ Collection for Quantis™ Plus MS
Citations
Catalog NumberIQLAAEGAAPFADBMBMAIQLAAEGAAPFADBMBKSIQLAAEGAAPFARBMBKPIQLAAEGAAPFADBMBHQWFLOW-62003
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Ionization Method(s)ESIInquireESI and HRAMHESIInquire
Mass AnalyzerOrbitrapOrbitrapOrbitrapOrbitrapInquire
Scanning SpeedInquireOTMSn up to 40 Hz ITMSn up to 45 HzUp to 22 Hz at resolution setting of 15,000 at m/z 200InquireInquire
Resolution7500 to 500,000 (FWHM) at m/z 2007500 to 500,000 (FWHM) at m/z 200Up to 240,000 at m/z 2007500-500,000 (FWHM) at m/z 200Inquire
DescriptionBuilt for small-molecule analyses, the Thermo Scientific™ Orbitrap IQ-X™ Tribrid™ mass spectrometer reveals your most complex chemical structures? with ultimate confidence, ease, and experimental versatility.One system, maximum insights
Today’s cutting-edge research pushes LC-MS to its limits. Obtaining high confidence insights to enable accurate resolution of subtle differences and avoid costly dead-ends is needed faster than ever before. The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
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The Thermo Scientific Orbitrap Exploris 240 mass spectrometer combines application flexibility with the performance to drive discovery and identification, plus receive the quantitative precision and accuracy you need to confidently scale up and achieve impact. With operational simplicity through ... Read MoreExcel at the most challenging of applications, including low level PTM analysis, multiplexed relative quantitation using isobaric tags, intact protein characterization, as well as MSn analysis of small molecules with the new Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer. This... Read MoreAn all-in-one LC-MS/MS workflow solution for toxicology. Increase productivity with SRM acquisition speeds enabling faster polarity switching of both positive and negative compounds. Triple quadrupole option includes experimentally obtained compound database and retention times of over 1100 ... Read More
QuantityEAEAEAEAEA
TypeOrbitrap Tribrid Mass SpectrometerInquireOrbitrap LC-MSInquireTox Explorer Collection
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