LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanySCIEXSCIEX
ItemX500R QTOF systemEcho® MS+ system
Citations
(7)
Catalog NumberX500R QTOFEcho MS+
Price
Ionization Method(s)Turbo V ion source with twin sprayer ESI probe
and twin sprayer APCI probe
Electrospray Ionization
Mass AnalyzerQTOFTriple Quad or TOF
Scanning SpeedUp to 25 Hz (25 spectra per second)Up to 3 samples per second
ResolutionEqual to or greater than 42,000 (FWHM) measured on the (M+6H)6+ charge isotope cluster for bovine insulin at m/z 956Inquire
DescriptionEngineered for standard biotherapeutic characterization analyses, the X500B QTOF system is a true benchtop instrument, with streamlined processing to get to a consistent, accurate view of your biologic. It is optimized for intact mass analysis, subunit analysis as well as high-quality peptide ... Read MoreThis ultra-high sample throughput system for Acoustic Ejection Mass Spectrometry (AEMS) delivers speed, scale, and reproducibility with unyielding data quality. The Echo® MS+ system leverages industry-leading quantitative MS technology from SCIEX to deliver a highly sensitive solution that can ... Read More
QuantityEAEA
Get Quote

Articles