LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanySCIEXSCIEXSCIEXSCIEXSCIEX
ItemIntabio ZT systemCitrine SystemEcho® MS+ systemSCIEX 7500+ SystemZenoTOF 7600 system
Citations
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(1)
Catalog NumberIntabio ZTEcho MS+SCIEX 7500+ SystemZenoTOF 7600
Price
Ionization Method(s)icIEFElectrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI)Electrospray IonizationOptiFlow® Pro Ion SourceAPCI and ESI modes
Mass AnalyzerTime of FlightTriple Quadrupole / QTRAP Hybrid (linear ion trap + triple quadrupole)Triple Quad or TOFTriple quadrupoleTOF
Scanning SpeedInquire1 ms MRM dwell times; 5 ms polarity switchingUp to 3 samples per second20,000 Da/sup to 25 Hz (25 spectra per second)
ResolutionInquireInquireInquireUp to 3100 for mass 922 in LIT mode 1000 Da/s (0.3 Da)
Tune to a peak width of 0.5 Da for TQ mode
Equal to or greater than 42,000 (FWHM) measured on the [M+6H]6+ charge isotope cluster for bovine insulin at m/z 956
DescriptionThe Intabio ZT system couples icIEF separation and UV detection with high-resolution mass spectrometry on the ZenoTOF 7600 system. Experience one integrated workflow with a single, accessible dataset containing the required information to make the right decisions, fast.

Features
  • Comprehensive
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The SCIEX Citrine MS/MS system is an in vitro diagnostic medical device providing the highest performance and reliability for demanding clinical diagnostics assays. Available in triple quadrupole and QTRAP versions, it delivers unparalleled sensitivity, high throughput, a wide dynamic range, and ... Read MoreThis ultra-high sample throughput system for Acoustic Ejection Mass Spectrometry (AEMS) delivers speed, scale, and reproducibility with unyielding data quality. The Echo® MS+ system leverages industry-leading quantitative MS technology from SCIEX to deliver a highly sensitive solution that can ... Read MoreInquireA powerful leap in proprietary innovation, this high-resolution accurate mass system combines the power of Zeno trap pulsing with EAD fragmentation technology (electron activated dissociation) to uncover structural information, previously inaccessible, and drive the limits of quantification ... Read More
QuantityEAInquireEAEAEA
TypeInquireTriple Quadrupole LC-MS/MS (IVD)InquireLC-MS/MSInquire
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