| Description | The LCMS-8065XE introduces innovative technologies that deliver exceptional performance with evolved, efficient and exact capabilities.
The instrument incorporates Shimadzu’s complete Ultra Fast Mass Spectrometry (UFMS) technology suite:
- World-class 5 msec positive/negative ion switching with
The LCMS-8065XE introduces innovative technologies that deliver exceptional performance with evolved, efficient and exact capabilities.
The instrument incorporates Shimadzu’s complete Ultra Fast Mass Spectrometry (UFMS) technology suite:
- World-class 5 msec positive/negative ion switching with zero signal loss
- Ultra-fast MRM acquisition up to 555 channels/sec
- Scanning up to 30,000 u/sec with maximum ion transmittance
- Advanced UF-Qarray™II & UF-Lens™ II ion guides for maximum transmission efficiency
New advancements include:
- StreamFocus Ionization Technology – The LCMS-8065XE features a low-dispersion nebulizer nozzle that dramatically reduces liquid droplet dispersion while maximizing ion intake efficiency. This breakthrough reduces nebulizer gas consumption by up to 7-fold compared to conventional ESI sources and achieves exceptional sensitivity improvements, particularly in negative mode.
- Enhanced IonFocus Performance – The evolved IonFocus unit utilizes a focusing electrode to selectively guide ions into the intake port while excluding neutral matrix components. This ensures sensitivity even when the ion spray is positioned further from the intake port, delivering superior robustness for long-term analysis.
- UFsweeper™ IV Collision Cell – The next-generation collision cell features a larger inlet lens diameter and an increased number of lenses for improved ion throughput, enhanced ion transmission, and dramatically improved sensitivity and quantitative precision.
- Performance Concierge – Automatically monitors system performance, provides proactive maintenance alerts, and reduces instrument downtime through predictive diagnostics. Peakintelligence for LCMS delivers revolutionary AI-driven peak detection with up to 67% reduction in manual review time and superior reproducibility across complex analyses.
The LCMS-8065XE excels across environmental monitoring, food safety, pharmaceutical analysis, clinical research, and industrial quality control applications.
It particularly excels for analysis of PFAS.
The LCMS-8065XE demonstrates remarkable capabilities with sub-ng/L detection limits for PFAS compounds in drinking water using direct injection.
The system delivers 3–48 fold sensitivity enhancement compared to previous generation instruments while maintaining exceptional stability – over 85% of initial response retained after more than 10,000 consecutive injections of complex wastewater samples (RSD <7%)
LabSolutions LCMS workstation software offers total operator support, from analysis to data processing.
The LabSolutions Connect/LabSolutions Insight platform supports the entire analysis workflow:
- Project file management
- Optimization of MRM and interface parameters
- Efficient verification of quantitative results
- Simple method and batch creation
- Verification of quantitative results
... Read More | Incorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050RX offers outstanding measurement speeds and quantitative performance.
Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated Incorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050RX offers outstanding measurement speeds and quantitative performance.
Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated electrospray source and ultra-efficient collision cell.
Combine with Shimadzu’s world-leading UHPLC systems for an unmatched level of performance.
Features:
- Ultrafast polarity switching (5 msec) – maintains constant quality and sensitivity with no loss of quantitative accuracy
- Ultra-high-speed scan rate of 30,000 u/sec – obtains high-quality mass spectra, even during high-speed analysis
- Ultrafast MRM transition speeds, up to 555 MRMs per second
- Heated ESI probe – promotes the ionization of wide range of targeted compounds
- CoreSpray™ gas delivery system – enhances reliability by increasing gas flow and improving nebulizer coaxiality
- High-efficiency CID cell – maintains signal intensity and suppresses crosstalk, even for high-speed or simultaneous multicomponent analysis
- Performance Concierge – Automatically monitors system performance, provides proactive maintenance alerts, and reduces instrument downtime through predictive diagnostics
- Easy maintenance – Changing the ESI capillary and the desolvation line (DL) can be quickly replaced without breaking vacuum
Intuitive LabSolutions software allows for simplified instrument control, diverse data handling, and integration with regulatory compliance requirements.
Optional LabSolutions Insight data review software, supporting review-by-exception, dramatically improves the speed and efficiency of multi-analyte data analysis.
In addition, LabSolutions MRM Connect automates MRM optimization to create high sensitivity quantitative LC-MS/MS methods.
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