LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemLCMS-9030 Quadrupole Time-of-Flight Mass SpectrometerLCMS-8045RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8050RX Triple Quadrupole LC/MS/MS Mass SpectrometerNexera Mikros Microflow Liquid Chromatography Mass Spectrometer SystemNexera QX Multiplex LC-MS
Citations
(9)
Figures
(2)
Catalog NumberLCMS-8050RXNexera MikrosNexera QX
Price
Ionization Method(s)ESI, APCIESI, APCIESI, APCI, Dual Ionization, Micro-ESIMicro-ESIESI, APCI, Dual Ionization
Mass AnalyzerQuadrupole Time-of-Flight (Q-TOF)Triple QuadrupoleQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rods
Scanning Speed100 Hz maximum acquisition rateUp to 15,000 Da/s30,000 u/secInquireInquire
Resolution30,000 FWHM0.1 Da (unit resolution)R < 0.7 u FWHMInquireInquire
DescriptionQ-TOF mass spectrometer integrating fast quadrupole technology with unique TOF architecture. Features UFaccumulation, UFgrating, UF-FlightTube with temperature control, and iRefTOF technologies for superior sensitivity, mass accuracy, and speed.InquireIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050RX offers outstanding measurement speeds and quantitative performance.
Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated
... Read More
Covering the complete range from micro (0.1 µL/min) to semi-micro (500 µL/min), Nexera Mikros allows operators to realize high sensitivity with the reliability and ruggedness of HPLC. A newly designed micro ESI source provides greater than ten times the sensitivity of standard UHPLC-MS ... Read MoreThe Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.

  • Multiple stream technology eliminates waiting for column equilibration and system
... Read More
QuantityInquireInquireEAEAEA
TypeQuadrupole Time-of-Flight (Q-TOF) LC-MS/MSTriple Quadrupole LC-MS/MSInquireInquireInquire
Get Quote

Articles