LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemLCMS-8045RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8050RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8060RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8065XE Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-9030 Quadrupole Time-of-Flight Mass Spectrometer
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Catalog NumberLCMS-8050RXLCMS-8060RXLCMS-8065XE
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Ionization Method(s)ESI, APCIESI, APCI, Dual Ionization, Micro-ESIESI, APCI, Dual Ionization, Micro-ESIESI, APCI (optional)ESI, APCI
Mass AnalyzerTriple QuadrupoleQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQuadrupole Time-of-Flight (Q-TOF)
Scanning SpeedUp to 15,000 Da/s30,000 u/secMax. 30,000 u/sec (in all scan modes) (0.1 u step: 300,000 data points/sec)Max. 30,000 u/sec (in all scan modes)100 Hz maximum acquisition rate
Resolution0.1 Da (unit resolution)R < 0.7 u FWHMR < 0.7 u FWHM and adjustable to 0.5 uR < 0.7 u FWHM and adjustable to 0.5 u30,000 FWHM
DescriptionInquireIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050RX offers outstanding measurement speeds and quantitative performance.
Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated
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The triple quad LCMS-8060RX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity.
A heat-assisted electrospray ionization probe delivers a highly efficient desolvation process that promotes the ionization of a wide range of target compounds
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The LCMS-8065XE introduces innovative technologies that deliver exceptional performance with evolved, efficient and exact capabilities.
The instrument incorporates Shimadzu’s complete Ultra Fast Mass Spectrometry (UFMS) technology suite:
  • World-class 5 msec positive/negative ion switching with
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Q-TOF mass spectrometer integrating fast quadrupole technology with unique TOF architecture. Features UFaccumulation, UFgrating, UF-FlightTube with temperature control, and iRefTOF technologies for superior sensitivity, mass accuracy, and speed.
QuantityInquireEAEAEAInquire
TypeTriple Quadrupole LC-MS/MSInquireTriple Quad LC-MS/MSTriple Quad LC-MS/MSQuadrupole Time-of-Flight (Q-TOF) LC-MS/MS
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