Inductively Coupled Plasma Mass Spectrometer (ICP MS)

Inductively coupled plasma mass spectrometers (ICP-MS) utilize inductively coupled plasma for sample ionization and an MS for ion separation and quantification. The low detection limits and high productivity possible with ICP-MS are particularly useful for trace metal analysis and environmental testing. Common components of an ICP-MS system include a sample introduction system, an ion source, a vacuum system, a collision reaction cell, ion optics, a mass spectrometer (often a quadrupole), and a detector. An analytical working range of nine orders of magnitude, detection limits below the ppt range, and aptitude for isotopic analysis are hallmarks of ICP-MS. ICP-MS instruments are commonly configured for routine analyses, high-matrix interference samples, or specific applications, such as work in the semiconductor industry or medical and forensic toxicology fields. Also, be sure to consider any desired customization options, such as chromatographic coupling or use with organic solvents.

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CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific iCAP RQplus ICP-MSThermo Scientific Element 2 HR-ICP-MSThermo Scientific Element XR HR-ICP-MSThermo Scientific Neptune Plus MC-ICP-MS
Price
Optical SystemArgon gas dilution (AGD) interfaceDouble-focusing sector field with physical interference separationDouble-focusing sector field with extended dynamic range detectorUp to 16 Faraday cups (laser-machined carbon, tera-ohm feedback resistors); up to 8 discrete-dynode electron multipliers (MIC); optional retarding potential quadrupole (RPQ) lenses
Mass AnalyzerSingle quadrupole; QCell collision/reaction cell with He KED; three AGD modes for online matrix dilutionDouble-focusing magnetic sector; three resolution settings: R = 300, 4,000, 10,000; magnet jump time <150 ms (7Li–²³8U–7Li)Double-focusing magnetic sector; three resolution settings: R = 300, 4,000, 10,000; triple detection (SEM + Faraday + filter lens); auto-switch to Faraday above SEM rangeDouble-focusing magnetic sector (MC-ICP-MS); mass range 1–256 u; low/medium/high resolution modes; independent source and detector slit settings
SensitivitySub-ppt capability with AGD technology>3×106 cps/ppb (¹¹5In) wet plasma with Jet Interface; >3–5×107 cps/ppb (¹¹5In) dry plasma>3×106 cps/ppb (¹¹5In) wet plasma with Jet Interface; >3–5×107 cps/ppb (¹¹5In) dry plasma10–20× increase in desolvation mode via jet interface
Dynamic RangeInquire>9 orders of magnitude (>10? cps linear dynamic range)>12 orders of magnitude (>10¹² cps linear dynamic range)High dynamic range with multi ion counting capability
ApplicationsEnvironmental analysis, food safety, pharmaceutical compliance, battery technology, petrochemicals, clinical researchSemiconductor and high-purity chemicals, environmental analysis, geochemistry, nanoparticle analysis, nuclear sciencesLaser ablation elemental mapping, semiconductor analysis, geoscience research, isotope ratio measurement, nuclear sciencesEarth sciences, geochronology, isotope ratio measurement, nuclear sciences, geochemistry, oceanography
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