Fluorescence imaging is one of our most powerful tools for the study of molecular biology and biochemistry, whether the technique in question is epifluorescence microscopy (excitation and observation of fluorescence from above the specimen); more complex confocal microscopy, which provides a clean, 3-D image; or fluorescence-lifetime imaging microscopy (FLIM), in which the lifetime of the fluorophore signal is measured.
Considerations when choosing a Fluorescence Imaging System:
Key elements of all fluorescence imaging systems include a light source, such as a xenon or mercury lamp, excitation and emission filters, and a dichroic mirror or beamsplitter. Sensitive detection of biological molecules is a major benefit of the technique, as is multicolor detection, which eliminates sample-to-sample variation and is both time and cost effective.
Discover and compare Fluorescence Imaging Systems:
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| Company | Thermo Fisher Scientific | Thermo Fisher Scientific |
| Item | CellInsight CX5 High-Content Screening (HCS) Platform | CellInsight CX7 Pro High-Content Screening (HCS) Platform |
| Citations | | |
| Catalog Number | CX51110 | HCSDCX7LEDPRO |
| Price | | |
| Description | The Thermo Scientific CellInsight CX5 is a compact benchtop high-content screening platform, offering automated quantitative cell analysis for every cell biology or screening lab. Designed for researchers looking to increase their screening throughput, the platform offers five multiplexable The Thermo Scientific CellInsight CX5 is a compact benchtop high-content screening platform, offering automated quantitative cell analysis for every cell biology or screening lab. Designed for researchers looking to increase their screening throughput, the platform offers five multiplexable wavelengths for fluorescence and white-light illumination for colorimetric samples. The system is compatible with 6-well through 1,536 microwell plates and can also be used to analyze slides and dishes. For groups requiring high-throughput screening, the CX5 can be automated with robotic handling for hands-free workflows. With proprietary autofocus and integrated plate-scanning intelligence methods, the CellInsight CX5 HCS Platform brings speed and accuracy to investigate cell populations and phenotypes without sacrificing sensitivity and resolution.
Applications - Intracellular to multicellular morphology measurements while measuring intensity of specific reporter molecules.
- Collect only the images and data you select and make multiple measurements per object, over time, if desired
- Measure subpopulations and reject undesired objects automatically
- Comprehensive pre-validated and user configurable image analysis without user scripting or programming
- Exploratory assay development tools and specific biology optimized tools built into the HCS Studio™ Cell Analysis Software
- Define biological thresholds for outputs based on control populations
- Ability to create multi-parameter gates from individual output measurements
... Read More | The Thermo Scientific CellInsight CX7 High-Content Screening Platform is an LED based platform that offers a choice of imaging modes to extract the information you need from your samples. Both well-by-well and channel-by-channel, you can select the right modes to read your sample—with the resolutionThe Thermo Scientific CellInsight CX7 High-Content Screening Platform is an LED based platform that offers a choice of imaging modes to extract the information you need from your samples. Both well-by-well and channel-by-channel, you can select the right modes to read your sample—with the resolution and dynamic range that results from the high performance of the optical train and sensitive camera. Use the entire fluorescence spectrum to optimize your assay and select either widefield or confocal optics for any channel. The CX7 Pro platform also offers 5-color brightfield options for colorimetric analysis of tissue sections. CellInsight CX7 Pro HCS Platform covers a broad range of assays for now and the future.
Features - Back-illuminated sCMOS camera offer a 95% peak quantum efficiency and -20°C cooling
- New validated applications including Cell Painting and FirePlex®-HT immunoassay
- Olympus X-line objective imaging to improve imaging quality and assay performance
- EurekaScan Finder double-pass functionality for on-the-fly seek and find of spheroids, tissue, and rare cellular events
- HCS Studio 5.0 with over 40 life science bio-applications and real-time analysis for fastest time-to-data possible
- 7-channel fluorescent imaging
- 5-channel bright-field imaging
- 7-channel confocal imaging
- Software and laser-based autofocus for consistent scan times
- Configured for fully automated plate handling and scanning
Applications - Use HCS Studio software for integrated instrument control and data analysis
- Achieve the fastest time to results by using intelligent acQuisition (iQ) real-time analysis feedback
- Addresses hundreds of assay types with flexible software and hardware tools
- Scan and analyze microscope slides or most SBS-standard format microplates
- Compatible with Molecular Probes fluorescent detection reagents
... Read More |
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