Gel electrophoresis instruments are used to separate nucleic acids and proteins based on their size and charge. Used in forensic, molecular biology, genetics, and microbiology labs, gel electrophoresis instruments are used to run and compare DNA samples. The two basic types of gel electrophoresis instruments available are horizontal and vertical. With the horizontal gel electrophoresis instrument, the sample is placed in wells on one side of the gel and is moved with an electric current toward the other side. The vertical version works in a similar manner, except the samples are loaded into the top and move toward the bottom.
Vertical gel electrophoresis instruments can resolve smaller fragments of DNA and accommodate larger sample sizes than horizontal instruments. Other things one may need to consider when choosing a gel electrophoresis instrument are the number and capacity of wells and if it has timed and/or untimed programs.
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Syngene
- Fluorescence imaging, gel documentation, DNA/RNA gel imaging, protein gel imaging
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Analytik Jena
- DNA analysis; RNA analysis; nucleic acid separation and identification
- Varies by model and comb selection
ProteinSimple
- Size-based purity and heterogeneity analysis of IgGs and other therapeutic proteins
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ProteinSimple
- Charge heterogeneity (icIEF), size and purity analysis (CE-SDS) of mAbs, ADCs, vaccines, VLPs
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ProteinSimple
- Charge heterogeneity, size/purity analysis, and charge isoform fraction collection for mAbs, ADCs, and other biologics
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Syngene
- Fluorescent DNA/RNA gel imaging, visible protein gel imaging, gel documentation, band excision, chemiluminescence (optional)
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Sebia
- Newborn hemoglobin disorders screening (Hb F, A, S, C, E, D, Bart's) from dried blood spots
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Syngene
- Chemiluminescence imaging, multiplex fluorescence Western blotting, stain-free imaging, gel documentation, in-vivo fluorescence, tissue sections, multi-well plates
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Bio-Rad Laboratories
- Protein gel imaging, nucleic acid gel imaging, western blotting, fluorescence, chemiluminescence, colorimetric detection, Stain-Free imaging
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Bio-Rad Laboratories
- Gel documentation, stained gel imaging, stain-free imaging, fluorescence gel imaging (ethidium bromide, SYBR dyes, Coomassie, Flamingo, Oriole, SYPRO Ruby)
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