Capillary electrophoresis instruments enable to the separation of charged molecules from each other. Unlike standard SDS-PAGE separation, capillary electrophoresis systems can provide molecule detection after separation through a light source and detector and the system can utilize high voltages without overheating the samples. Applications for capillary electrophoresis instruments include pharmaceutical (i.e. digest analysis of biopharma drugs; peptide mapping), life science (i.e., protein/peptide separation, DNA analysis, and PCR product analysis, chemical (i.e. raw material analysis), forensics (i.e. drug and explosive analysis), environmental (i.e. pesticide analysis) and food/beverage (i.e. as organic acid analysis).
Consideration when purchasing a capillary electrophoresis system:
Capillary electrophoresis provides additional advantages over other analysis methods, like HPLC, GC, SDS-PAGE, which include speed, cost of analysis, and easy method development. First consideration is the type of system required. There are several methods of capillary electroseparation, which include capillary zone electrophoresis, capillary isoelectric focusing, capillary gel electrophoresis, and more. Second consideration is the system’s throughput; how many samples can the instrument run.
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Bio-Techne
- Capillary Electrophoresis (CE) Instrument — imaged capillary isoelectric focusing (icIEF) and CE-SDS
- Protein purity, identity and charge heterogeneity analysis; cIEF (charge variants, pI determination); CE-SDS (size-based purity, heavy chain / light chain / NGHC content); mAbs, ADCs, fusion proteins, peptides, vaccines, virus-like particles; biopharmaceutical QC/QA, GMP/21 CFR Part 11 compliance
- Maximum 100 injections per batch (cIEF); maximum 48 injections per batch (CE-SDS PLUS); maximum 96 injections per batch (Turbo CE-SDS). Sample tray options: 96-well plates or 48 vials
Bio-Techne
- Capillary Electrophoresis (CE) Instrument — imaged capillary isoelectric focusing (icIEF) only
- Charge heterogeneity and identity analysis (cIEF/icIEF); pI determination; charge variant profiling of mAbs, ADCs, vaccines; biopharmaceutical QC/QA and method development; GMP/21 CFR Part 11 compliant environments
- 100 guaranteed injections per cartridge, 200 maximum; maximum 100 injections per batch. Sample tray options: 96-well plates or 48 vials
Bio-Techne
- Capillary Electrophoresis (CE) Instrument — CE-SDS (size-based separation) only
- IgG purity and heterogeneity analysis by size (CE-SDS); heavy chain, light chain, and NGHC content determination; mAb characterization; biopharmaceutical QC/QA and method development; GMP/21 CFR Part 11 compliant environments
- CE-SDS PLUS: maximum 48 injections per batch; Turbo CE-SDS: maximum 96 injections per batch. Sample tray options: 96-well plates or 48 vials
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Companies that sell Capillary Electrophoresis Instrument
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- Amazing Fluorescence-based Electrophoresis Unit
Thermo Fisher Scientific
This analyzer is a capillary having fluorescence based electrophoresis unit which is very excellent and amazing to quantify the DNA molecules. Its very helpful for a molecular biologists and very easy... Read Review - Accurate, Simple, and Highly Flexible
Thermo Fisher Scientific
This machine is capable of providing accurate results, very easy and simple to use with flexible working capacity. This machine can handle samples very effectively and is very useful for molecular ... Read Review