In Raman microscopy, also called confocal Raman microscopy, an optical microscope and a Raman spectrometer are combined into one instrument in order to provide high resolution images of small samples. This high resolution imaging has applications that include materials science, earth science, cell biology, medicine, cosmetics, and art analysis.
A Raman microscope consists of a basic optical microscope, a Raman spectrometer, a laser, a light source, and a detector such as a CCD camera. The optical microscope uses light to magnify and identify samples while the Raman spectrometer scatters light and measures the excitation vibration. When selecting a microscope, it is important to consider the qualities of each of the microscope's components and their optimal configuration for a particular application.
Find, compare, and request a quote for Raman and confocal Raman microscopes across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.
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| Company | Oxford Instruments | Oxford Instruments | Oxford Instruments | Oxford Instruments | Oxford Instruments |
| Item | TrueSurface – Topographic Raman Imaging | alphaCART – Mobile Raman System | ParticleScout – Raman-based Particle Analysis | RISE Microscopy – Raman Imaging-SEM | witec360 Raman Microscope |
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| Catalog Number | TrueSurface™ | | ParticleScout™ | RISE™ Microscopy | |
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| Description | The patented TrueSurface Microscopy option for witec360 microscopes enables confocal Raman imaging guided by surface topography to maintain an optimal focus throughout a measurement.
The pioneering topographic Raman imaging technology uses an integrated optical profilometer to provide one-pass The patented TrueSurface Microscopy option for witec360 microscopes enables confocal Raman imaging guided by surface topography to maintain an optimal focus throughout a measurement.
The pioneering topographic Raman imaging technology uses an integrated optical profilometer to provide one-pass simultaneous operation.
- Enables 3D chemical characterisation of rough, inclined or irregularly shaped samples.
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• Compensates for variations during measurements with long integration times.
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• Features variable offset from the sample surface.
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• Integrates seamlessly with Raman, PL, white-light microscopy.
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• Further reduces sample preparation effort.
... Read More | alphaCART is Oxford Instruments' mobile, confocal Raman system for all applications that require bringing the lab to the sample, including specimens that don’t fit under a microscope and fragile or precious objects that can’t be removed from secure locations.
The system's high confocality and alphaCART is Oxford Instruments' mobile, confocal Raman system for all applications that require bringing the lab to the sample, including specimens that don’t fit under a microscope and fragile or precious objects that can’t be removed from secure locations.
The system's high confocality and signal sensitivity also allow measurements through protective glass and windows, which enable studies of gases or chemical processes inside reaction chambers and other enclosures.
- Freely positionable, fibre-coupled Raman probe.
- High spectral and spatial resolution, confocality, and signal sensitivity.
- Sample survey with white-light illumination and colour video camera.
- Objective, laser and spectrometer configuration options.
- Rolling flight case containing and protecting all components (optional).
- Polarisation-sensitive measurements (optional).
- Full compatibility with the witec360's upgrades and accessories.
... Read More | ParticleScout is an advanced particle analysis tool for witec360 Raman microscopes that finds, classifies and identifies microparticles over even large sample areas.
User-defined categorization of particles by shape and size offers access to wide-ranging properties, and the results of the ParticleScout is an advanced particle analysis tool for witec360 Raman microscopes that finds, classifies and identifies microparticles over even large sample areas.
User-defined categorization of particles by shape and size offers access to wide-ranging properties, and the results of the measurement are then presented in a report that provides a comprehensive description of the sample.
ParticleScout features the most flexible and useful sample survey capabilities available.
- White-light Microscopy: Bright field/dark field, transmission/reflection.
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Image Stitching: Scans of many sample areas can be combined into one measurement for a large-area overview of widely distributed particles.
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Focus Stacking: This unique capability dramatically increases the depth of focus for sharp and defined particle imaging.
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Integration time optimisation – reduces measurement time and minimizes the effects of fluorescence.
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Vignetting correction – ensures uniform brightness throughout the image plane.
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Smart zoom – displays particle information dynamically depending on viewed area.
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Sample area targeting – allows the selection of multiple regions of interest for each investigation.
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Dark-field, bright-field, epifluorescence and transmission sample illumination – provides the best option for each type of particle.
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Round sample wedge sectioning – allows the selection of an area for data acquisition, typically on a filter, that can be extrapolated to represent the whole.
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Smart separation of particles – differentiates materials in densely packed, heterogeneous samples.
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• Quantitative report formatting – presents data using table, bar graph histogram and pie chart templates for ease and clarity.
... Read More | RISE Microscopy is a novel correlative microscopy technique that combines confocal Raman Imaging and SEM to link ultra-structural surface properties with molecular compound information.
The RISE Microscope combines all features of a stand-alone SEM and the witec360 confocal Raman imaging microscopeRISE Microscopy is a novel correlative microscopy technique that combines confocal Raman Imaging and SEM to link ultra-structural surface properties with molecular compound information.
The RISE Microscope combines all features of a stand-alone SEM and the witec360 confocal Raman imaging microscope within one instrument.
- Quick and convenient switching between Raman and SEM measurement.
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Automated sample transfer from one measuring position to the other.
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Integrated software interface for user-friendly measurement control.
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Correlation of the measurement results and image overlay.
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No compromise in SEM and Raman imaging capabilities.
... Read More | The witec360 Raman microscope, successor to the pioneering alpha300 series, sets new standards in performance and broadband capability. Its fundamentally modular design provides immediate and long-term value with easy onboarding for Raman newcomers and the versatility to keep pace with varied and The witec360 Raman microscope, successor to the pioneering alpha300 series, sets new standards in performance and broadband capability. Its fundamentally modular design provides immediate and long-term value with easy onboarding for Raman newcomers and the versatility to keep pace with varied and quickly evolving applications.
- Acquire research-grade results: Optimised optics throughout the entire beam path deliver class-leading speed, sensitivity, and resolution for leading-edge research and development.
- Experience unprecedented versatility: Broadband capabilities provide the spectral flexibility needed for demanding research tasks and diverse applications in multi-user facilities.
- Gain comprehensive insight: Seamless integration of imaging techniques enables the correlation of chemical and structural properties for a more thorough understanding of samples.
- Configure your microscope for current and evolving experiments: Modular design offers a wide range of capabilities and upgrade options to deliver tailored solutions and scalability to match your institution’s requirements and resources.
- Enhance productivity with intelligent automation: Advanced hardware automation and intuitive software simplify data acquisition and analysis for operational efficiency and fast onboarding of users with different experience levels.
- Ensure consistency and transparency: Multi-user management, internal calibration, automated reporting, and streamlined analysis facilitate reproducibility and support institutional and regulatory compliance.
... Read More |
| Measurement Mode(s) | Topographic Raman Imaging | Confocal Raman Imaging Microscopy | Raman-based particle analysis | Raman Imaging-SEM | Confocal Raman Imaging Microscopy |
| Focal Length | less than 1 µm | Inquire | Inquire | Inquire | Inquire |
| Detector(s) | Optical Profilometer | CCD/EMCCD | CCD/EMCCD | CCD/EMCCD | CCD/EMCCD |
| Laser Sources | Multiple Laser Sources | Multiple Laser Sources | Multiple Laser Sources | Multiple Laser Sources (up to six) | Multiple Laser Sources |
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