The complex sample matrix of cannabis yields a variety of extraction methods for cannabis sample preparation. There is also an impressive diversity of product types including flower, extracts and edibles that require its unique extraction and cleanup protocols. Recommended methods to be familiar with include dSPE and QuEChERS. In this month’s Buyers Guide, we will focus and insights on cannabis sample preparation technologies.
Used to determine water concentration, Kar Fischer titrators are great for reactivity, stability and quality testing. The two primary methods of this titration are volumetric and coulometric titration. When choosing a titrator make sure you access which method is needed, duration of titration, and level of automation provided in prospective units.
The top pick for Karl Fischer titrators is the EasyPlus™ Series Titrators from Mettler-Toledo GmbH .
Utilizing high-speed spinning, centrifuges separate desired products from samples based on their density. When choosing a centrifuge, it is imperative to determine the speed needed to separate samples, volume desired, and whether refrigerated units are necessary.
The top pick for laboratory centrifuges is the NuWind Multi-Application Bench Top Ventilated or Refrigerated Centrifuges from NuAire.
Evaporators are used to remove liquids from samples and in the case of cannabis sample preparation an invaluable instrument for end-product formulation. Evaporators can also be utilized to remove organic solvents relying on motion, heat, and gas to dry samples. Three primary evaporator types are nitrogen, vacuum, and rotary evaporators. Key considerations include the application used, size, and speed of evaporation.
The top pick for laboratory evaporators is the KNF Rotary Evaporators from KNF Neuberger, Inc.
Laboratory mills and grinder reduce the particle size of samples by grinding and homogenizing a variety of sample types. In the case of cannabis, there are many sample types that will need milling and grinding due to the fibrous nature of the product. Key considerations include the power of the mill or grinder needed, speed, cooling ability, maintenance protocols and ease.
The top picks for laboratory mills and grinders are Knife Mill PULVERISETTE 11 from FRITSCH GmbH and Distek's PrepEngine.
Microwave digestion aims to breakdown samples in preparation for elemental analysis. Digestions are accomplished efficiently by directing microwave energy into closed vessels, increasing sample throughput. Key considerations include the rate of digestion needed, temperature, pressure, maximum microwave power, and parameter monitoring systems.
The top pick for microwave digestion technologies is TOPwave Sample Preparation System from Analytik Jena.
Chris Cicinelli is the Associate Editor for Labcompare.