Raman Spectroscopy

Raman spectroscopy is a way to get information on the vibrational and rotational frequencies in a sample. Pharmaceutical, material science, bioscience, forensics, and nanotechnology are some of the industries that use Raman spectroscopy to analyze the chemical makeup of a given sample. Raman spectroscopy can identify a molecule, show the dispersion of ingredients in a tablet, monitor biological tissue without surgery, or determine the components of historical documents or works of art.

There are several types of Raman spectroscopy, including transmission Raman, which can analyze bulky powders or biological tissues and is used in the pharmaceutical industry for quality control and for diagnosing some medical conditions, and spatially offset Raman spectroscopy (SORS), which allows analysis to occur even when there is a layer covering the analyte.

Considerations for purchasing a Raman system

To choose the correct Raman spectroscopy system, you must first know what kind of materials are to be analyzed. There are systems that enhance the signals of gold and silver, those that “see” through layers that conceal what's inside of them, and systems that can be used to monitor anesthesia during surgery. If the analysis is to be done in your lab, a benchtop model may work best, but if analysis is to be done in the field, there are handheld systems that may be better suited for your needs.

Recent updates in the market

One of the newest uses for Raman spectroscopy is in airport security. It can be used to detect threats concealed under clothing and in bags. One of the upsides of this technology in airports is that by using a SORS system, analysis of liquids still in their containers can be performed. The use of this type of Raman spectroscopy could allow passengers to once again bring liquids on flights.