T Cell Receptor (TCR) is a key membrane protein expressed by T cells that is essential to make the interaction with target cells and especially their Class I HLA proteins. In case of mismatches between Class I HLA, T cells will be activated and will eliminate target cells considered as "non self". ... read more

I perform a lot of electroporation experiments, especially with CRSIPR-Cas9 RiboNucleoProtein (RNP) complex. I use different cell lines to do so such as HEK, immortalized B cells but also primary T cells and iPSCs. Having a good viability after electroporation is essential with primary cells to be ... read more

Efficient separation of PBMCs in fresh blood is essential to perform experiments in immunology for example. When I use this product, I put 12.5mL of this in a 50mL falcon and then I add the fresh blood drop by drop leaning the falcon. This step is not very easy to achieve properly so after ... read more

HLA-DR protein is part of the Class II HLA membrane protein. Those proteins are recognized by CD4 T cells and can be the origin of a rejection in case of cell therapy of graft for example. This antibody allows me to quantify the HLA-DR expression of my cell lines but can also be helpful to separate ... read more

MICA and MICB are membrane proteins that play a role in sending activating signals to NK cells. Depending on the cell type and also the state of the cells, these proteins may be more or less expressed at the membrane. With this product, you can easily quantify this expression. However, I found ... read more