HLA-C membrane protein is part of the Class I HLA proteins that play a huge role in the mechanism of rejection. HLA-C is recognized by CD8 T cells that are triggered in case of HLA mismatches between donor and recipient. In general, I use Class I HLA antibody to determine the level of expression of... read more

I perform a lot of CRISPR-Cas9 genome editing experiments and I started recently to insert point mutations instead of simply doing a knock-out. This product does increase the rate of HDR events which is quite low in general. I recommend using this product but be careful with the incubation time as ... read more

I perform CRISPR-Cas9 genome editing on different type of cells such as HEK293T, T cells and B cells. One very important result of those experiments is the knock-out efficiency. Through my experiments, I noticed a much higher efficiency using this product during electroporations of Cas9 RNP. Thus, I... read more

I used this product to quantify supernatant fluorescence after co-culturing NK cells with fluorescent target cells such as HEK293T and B-EBV cells to highlight a difference in immune response. I recommend this product as it is very easy to use, even if it is disposable. read more