HPLC Detector

An HPLC detector is used to analyze the components of the eluted mixture that is collected after being run through an HPLC column. Differences in detector type are based on what is being detected. Detection can be done by measuring absorbance, changes in reflex indices, molecular weight, and fluorescence among others. When selecting a detector, it is important to consider the sample type being analyzed. Some sample types will not work or will have lower sensitivity on particular detectors. Also of consideration is the type of information that is being sought by the analysis and what method will be used when running the column, for example, some detectors will work with the gradient method while others will not.

Find, compare, and request a quote for HPLC detectors across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.

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FlowStar&sup2; LB 514 Radio HPLC Detector
Berthold Technologies GmbH & Co. KG
  • Type:
    Radio Flow Detector
  • Detector(s):
    State-of-the-art ultrasensitive dual 2“ PMT detection system with random coincidence counting and luminescence subtraction.
  • Applications:
    Drug metabolism studies, drug synthesis and purity, toxicological studies, purification of radio chemicals,
    development and Quality Control of radio chemicals, quality Control of radiolabelled antibodies and proteins
HERM LB 500 with fLumo detector Radio HPLC Detector
Berthold Technologies GmbH & Co. KG
  • Type:
    Luminescence
  • Detector(s):
    Low noise photon counting 1 inch PMT
  • Applications:
    Quality control, PET quality control, and other applications.
HERM LB 500 with NaI detector Radio HPLC Detector
Berthold Technologies GmbH & Co. KG
  • Type:
    Radio Flow Detector
  • Detector(s):
    State-of-the-art ultra sensitive PMT coupled 1 inch NaI detector
  • Applications:
    125I quality control, 18F quality control, 68Ga quality control, Gamma metabolite studies (all gamma isotopes)
LC-4000 Circular Dichroism Detector
JASCO
  • Type:
    Circular Dichroism Detector
  • Detector(s):
    Circular Dichroism
  • Applications:
    Inquire
Citations:
(7)
LC-4000 Optical Rotation Detector
JASCO
  • Type:
    Optical Rotation Detector
  • Detector(s):
    Optical Rotation
  • Applications:
    Inquire
Citations:
(7)
LC-4000 Series Fluorescence Detectors
JASCO
  • Type:
    Fluorescence Detector
  • Detector(s):
    Fluorescence
  • Applications:
    Inquire
Citations:
(26)
LC-4000 Series PDA Detectors
JASCO
  • Type:
    Diode Array Detector
  • Detector(s):
    Diode Array
  • Applications:
    Inquire
Citations:
(112)
LC-4000 Series Refractive Index Detectors
JASCO
  • Type:
    Refractive Index Detector
  • Detector(s):
    Refractive Index
  • Applications:
    Inquire
Citations:
(41)
LC-4000 Series UV/Visible Detectors
JASCO
  • Type:
    UV-Visible Detector
  • Detector(s):
    UV-Visible
  • Applications:
    Inquire
Citations:
(90)
CDD-10Avp HPLC Conductivity Detector
Shimadzu
  • Type:
    Conductivity Detector
  • Detector(s):
    Inquire
  • Applications:
    Environmental, water testing, and food laboratories.
Citations:
(56)
ELSD-LTIII Low Temperature Evaporative Light Scattering Detector
Shimadzu
  • Type:
    Low Temperature ELSD
  • Detector(s):
    Photodiode
  • Applications:
    General-purpose universal detector that can even detect components with no UV absorption, such as carbohydrates, lipids, surfactants, and synthetic polymers (excluding some volatile compounds).
SPD-M40 HPLC/UHPLC Photodiode Array Detector
Shimadzu
  • Type:
    Photodiode Array Detector
  • Detector(s):
    Photodiode Array
  • Applications:
    Inquire
Citations:
(47)
DAWN&trade; Multi-angle Light Scattering (MALS) Instrument
Waters | Wyatt Technology
  • Type:
    MALS and optional DLS
  • Detector(s):
    High-gain, high-dynamic-range photodiodes at 18 angles for MALS; optional avalanche photodiode that may be placed at any of four angles for DLS.
    Fluorescence-blocking filters available for use with analytes that fluoresce when illuminated at the MALS wavelength.
  • Applications:
    With standard SEC/GPC or EclipseTM (FFF system): determination of distributions of molar mass, size, conformation, conjugation ratio and particle concentration. With Calypso composition-gradient system: label-free characterization of biomolecular interactions including self- and hetero-association as well as non-specific interactions.
microDAWN&trade; Multi-Angle Light Scattering Instrument for UHP-SEC-MALS
Waters | Wyatt Technology
  • Type:
    MALS and optional DLS
  • Detector(s):
    High-gain, high dynamic range, static light scattering detectors at 3 angles
  • Applications:
    With SEC/GPC: determination of distributions of absolute molar mass, size, conformation, conjugate ratio.
Citations:
(1)
microOptilab&trade; Refractive Index Detector for UHPLC
Waters | Wyatt Technology
  • Type:
    Refractive Index Detector
  • Detector(s):
    Differential Refractive Index (dRI)
  • Applications:
    Measure concentrations of all types of samples in almost all solvents
Citations:
(1)
miniDAWN&trade; Multi-Angle Light Scattering (MALS) Detector for SEC-MALS
Waters | Wyatt Technology
  • Type:
    MALS and optional DLS
  • Detector(s):
    High-gain, high-dynamic range photodiodes at 3 detection angles for MALS. Optional avalanche photodiode for simultaneous dynamic light scattering measurements.
  • Applications:
    With SEC/GPC: determination of distributions of absolute molar mass, size, conformation, conjugate ratio. With Calypso CG-MALS: characterization of biomolecular interactions.
Citations:
(333)
Optilab&trade; Refractive Index Detector for HPLC/GPC
Waters | Wyatt Technology
  • Type:
    Refractive Index Detector
  • Detector(s):
    Differential Refractive Index (dRI)
  • Applications:
    GPC/SEC analysis of macromolecules by SEC-MALS
Citations:
(>1k)
WyattQELS™ Light Scattering Detector Module
Waters | Wyatt Technology
  • Type:
    Dynamic Light Scattering
  • Detector(s):
    Avalanche photodiode coupled to a multimode optical fiber
  • Applications:
    High-resolution size distributions with fractionation by SEC or FFF; conformation when combined with MALS molar mass and/or size data
Citations:
(46)
RID-20A Refractive Index Detector
Shimadzu
  • Type:
    High-Sensitivity Refractive Index Detector
  • Detector(s):
    High-Sensitivity Refractive Index Detector
  • Applications:
    Inquire
Citations:
(313)
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JASCO
FP-4020 / FP-4025
1
1 Figure from 26 Publications
Shimadzu
CDD-10Avp
2
1 Figure from 56 Publications
Shimadzu
RID-20A
5
1 Figure from 313 Publications
Showing 3 of 3 products
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  • Berthold Technologies GmbH & Co. KG
  • JASCO
  • Shimadzu
  • Waters | Wyatt Technology
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