High-performance liquid chromatography (HPLC) systems are used to analyze and/or purify liquid mixtures. Analytical HPLC systems are used in the food safety, pharmaceutical, and manufacturing industries, as well as in medical and research laboratories. Two of the most common types of analytical HPLC systems are normal phase HPLC and reversed phase HPLC. Normal phase uses a polar stationary phase and a non-polar mobile phase to separate components of a mixture, while reversed phase HPLC uses phases with the opposite polarities of normal phase HPLC. The sample liquid is mixed with the mobile phase and run through a column that contains the stationary phase. The way the sample moves through the column is the basis for the analysis.
Considerations for purchasing an Analytical HPLC System
To determine which analytic HPLC system is the best fit for your lab, decide which features will be needed. Multi-solvent or multi-column analysis, stationary phase pore size, possible pump pressures, possible flow rates, and number of wavelength detectors are all factors that can vary.
Find, compare, and request a quote for analytical HPLC systems across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.
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Select up to 5 products from below to compare or request more information.
PerkinElmer
- PDA (190-800 nm), Multiwavelength UV/Vis, Single Wavelength UV/Vis, Fluorescence, Refractive Index
- 0.001-10 mL/min
- 10,000 psi (690 bar)
Inquire
PerkinElmer
- PDA (190-800 nm), Multiwavelength UV/Vis, Single Wavelength UV/Vis, Fluorescence, Refractive Index
- 0.001-2 mL/min
- 18,000 psi (1,241 bar)
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PerkinElmer
- Coupled with NexION ICP-MS (speciation detection)
- 0.01-10 mL/min
- ~6,200 psi (420 bar)
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Polymer Char
- Infrared Detection, Viscometer
- Inquire
- Inquire
Polymer Char
- Infrared Detector IR4
- Inquire
- Inquire
Polymer Char
- Infrared Detection, Viscometer
- Inquire
- Inquire
SCIEX
- UV-VIS and photodiode array detectors
- 0.0001 to 3.0000 mL/min (145 to 15,200 PSI)
3.0001 to 5.0000 mL/min (145 to 11,600 PSI)
5.0001 to 10.0000 mL/min (145 to 3190 PSI) - 15,200 PSI (1048 bar)
SCION Instruments
- Ultraviolet (UV), Diode Array Detector (DAD), Fluorescence (FL) and Refractive Index (RI)
- Usual: 0.2 to 3.0mL/min
Max.: 10mL/min (solvent: pure water) - 600 Bar quaternary pump with 6-channel degassing and Low Pressure Gradient mixing options
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Shimadzu
- UV/VIS, PDA, RI, Fluorescence, ELSD, LCMS
- 0.0001 to 10 mL/min
- 70 MPa
Shimadzu
- UV, PDA, ELSD, Fluorescence, RID, Conductivity
- 0.0001 – 5 mL/min (1.0 – 44 MPa); 5 – 10 mL/min (1.0 – 22 MPa)
- 44 Mpa
Shimadzu
- Inquire
- 0.0001 to 2.0000 mL/min
- 130 MPa
Thermo Fisher Scientific
- Choices include: Vanquish Charged Aerosol Detector, Vanquish Diode Array Detector, Vanquish Fluorescence Detector, Vanquish Multiple Wavelength Detector, Vanquish Variable Wavelength Detector, Refractive Index Detector, Mass Spectrometer.
- 0–10 mL/min
- 700 bar
Waters | Wyatt Technology
- PDA Detector, TUV Detector
- 0.001 to 10,000 mL/min
- 12,000 psi
Waters | Wyatt Technology
Hitachi High-Tech America, Inc.
- UV Detector, UV-Vis Detector, Diode Array Detector, Fluorescence Detector, RI Detector, MS Detector
- 0.001 to 9.999 mL/min
- up to 60 MPa
Icon Scientific
- LED single or dual wavelength, Variable wavelength UV/VIS, Multi-wavelength UV/VIS, Diode Array, Refractive Index (configurable)
- 0.002 - 10.0 mL/min (based on ANSER PMP-3010 pump)
- 85 MPa / 850 bar / 12,300 psi (UHPLC configuration, based on PMP-3010)
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Icon Scientific
- Double-beam photometer, Multi-wavelength UV (1-2 variable wavelength channels)
- Inquire
- Inquire
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KNAUER
- UVD, MWD, DAD, RID, FLD, ELSD, MS
- 0.001–5 mL/min
- 1240 bar / 18,000 psi
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KNAUER
- UVD (VWD, MWD, DAD), RID, FLD, ELSD, MS
- 0.001–10 mL/min
- 862 bar
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KNAUER
- Compatible with all common HPLC detectors including MS/MS
- Inquire
- 1240 bar
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