A gel permeation chromatograph (GPC) is used to separate the components of a sample by size, this is known as size-exclusion chromatography (SEC).
GPC systems are widely used to analyze polymers and proteins in manufacturing, chemistry, and biology labs for quality control and analysis. GPC systems are composed of porous beads (the gel) inside a column, a pump to move the sample and eluent through the column, and a detector to detect when different analytes are eluted through the column. The detectors can be concentration sensitive or molecular weight sensitive.
Each gel permeation system has a range of sizes it can detect based on the pore sizes of the beads in the column, so before deciding on a system make sure you know the parameters you need. There are different types of porous beads that have varying affinities for materials and it is best for the gel to have a low affinity for the material you wish to analyze.
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Gilson Inc
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Polymer Char
- High Temperature Gel Permeation Chromatograph
- Infrared Detector, Viscometer Detector, Light Scattering Detector
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- 40ºC to 250ºC
Polymer Char
- Compact High-temperature GPC
- Infrared Detector, Viscometer
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- 40ºC to 250ºC
Shimadzu
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- Refractive Index
- 0.0001 to 10 ml/min
- [RT + 10C] to 85C
Shimadzu
- Gel Permeation Chromatography (GPC) / SEC
- Refractive Index Detector (RID), UV Detector, Photodiode Array Detector (PDA, 220-400 nm)
- 0.0001 to 10.0000 mL/min (model dependent; 0.0001-3.0000 mL/min at max pressure)
- Room temperature -10 C to 85 C (up to 100 C on high-pressure lite model)
Waters | Wyatt Technology
- Advanced Polymer Chromatography (APC) / GPC / SEC
- Refractive Index (RI), Ultraviolet (UV), Photodiode Array (PDA), Light Scattering (LS), Viscometry (IV)
- 0.010 to 2.20 mL/min
- 4.0 °C to 90.0 °C
Waters | Wyatt Technology
- HPLC / GPC / SEC
- TUV, PDA, FLR, RI, ELS, EC
- 0.001 to 5.000 mL/min
- 4 to 90 °C
KNAUER
- GPC Cleanup / Sample Preparation System
- UV
- 0.01 - 10 mL/min
- 5 - 85 °C
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KNAUER
- Analytical GPC/SEC System
- RI, UV, ELSD, PDA, FLD, ECD
- 0.001 - 10 mL/min
- 5 - 85 °C
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KNAUER
- Analytical GPC/SEC System
- RI, UV, ELSD, PDA, FLD, ECD, MS
- 0.001 - 10 mL/min
- 5 - 85 °C
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KNAUER
- Semi-Preparative GPC/SEC System
- RI (standard and high-flow), UV
- 0.01 - 50 mL/min
- 5 - 85 °C
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Tosoh Bioscience
- Integrated GPC System
- Dual Flow Refractive Index (RI), optional UV (195-350 nm), optional Light Scattering, optional Viscometry
- 0.010 to 2.000 mL/min (0.001 mL/min steps)
- 40 °C to 60 °C
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