Isothermal titration calorimetry is an analytical technique that measures heat discharge along a bimolecular reaction. Often used to determine the thermodynamic parameters associated with a binding event, isothermal titration calorimeters (ITC) can analyze binding affinity, stoichiometry, enthalpy change, and numerous other parameters. With uses in biochemistry, pharmaceutical, and other industries, isothermal titration calorimeters are an essential instrument while studying molecular interactions. Isothermal titration calorimeters offer excellent long-term temperature stability while providing more automation to increase laboratory throughput while reducing the need for analysts' time. When comparing different models of ITC be sure to consider the sensitivity, accuracy, and temperature control systems to allow for fine-tuning of sample analysis.
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Malvern Panalytical
- 2°C to 80°C
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TA Instruments
- 2 to 80°C
- 0.00005°C at 25°C
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TA Instruments
- 2 to 80°C
- 0.0002°C @ 25°C
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TA Instruments
- 4 to 150 °C
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- less than ± 100 µ °C/24h
TA Instruments
- 4 to 150 °C
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- < ± 100 µ°c/24h ±="" 100=""> ± 100 µ°c/24h>
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- Low Volume & Highly Sensitive Calorimeter
Malvern Panalytical
The MicroCal PEAQ-ITC is an excellent instrument for the label-free, in-solution testing of all binding parameters in one experiment. The calorimeter delivers high-quality data relating to the ... Read Review - Highly Recommended for Determining Affinity and Stoichiometry
Malvern Panalytical
The MicroCal PEAQ-ITC is one of the best inexpensive and good instruments on the market for determining binding affinity. The use of the instrument is very easy as compared to other ones. The thing I ... Read Review - Highly recommended
Malvern Panalytical
We deem the PEAQ very effective for validating binding, assess stoichiometry, protein QC, identifying different binding mechanisms in closely related compounds.
PEAQ is a low volume isothermal ... Read Review