| Description | Rat midbrain neurons (RMbN) are obtained from the midbrain of normal embryonic rats (the 15th day of pregnancy) by a standardized method. When cultured under the recommended conditions, RMbN forms a tree shape and complex formation within one week. The neurite network. RMBN is positive for βIIIRat midbrain neurons (RMbN) are obtained from the midbrain of normal embryonic rats (the 15th day of pregnancy) by a standardized method. When cultured under the recommended conditions, RMbN forms a tree shape and complex formation within one week. The neurite network. RMBN is positive for βIII-tubulin.
The midbrain is a small part of the brain, but plays an important role in the visual and auditory systems, motor control, alertness, sleep/wake and temperature regulation. It contains the substantia nigra, which is a dark area with a large number of dopaminergic neurons, which is closely related to motivation and habits. Midbrain atrophy and diseases seen in diseases such as Parkinson's disease, familial amyotrophic lateral sclerosis, and progressive supranuclear palsy can affect balance, gait, and muscle control. Studying midbrain neurons under those disease conditions will enable people to better understand disease mechanisms, physiopathology, and progress in drug development and treatment. The culture of midbrain neurons can be used in a variety of experiments, including toxicity tests, immunostaining, live cell imaging, co-culture, electrophysiology, etc.... Read More | Creative Biolabs' Neuropathy Frozen Tissue Panels are designed for the study of Alzheimer's disease, Parkinson's disease, dementia, multiple sclerosis, progressive supranuclear palsy (PSP) and depression. | Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. BacteroidesBacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.... Read More | iNeuMito™ biosensor is a mitochondrial calcium flux sensor. These cells are engineered to express iNeuMito™ biosensor, which has been developed to use a highly sensitive fluorescence-based biosensor as a reporter gene to monitor mitochondrial calcium flux and cytotoxicity. Excitation = iNeuMito™ biosensor is a mitochondrial calcium flux sensor. These cells are engineered to express iNeuMito™ biosensor, which has been developed to use a highly sensitive fluorescence-based biosensor as a reporter gene to monitor mitochondrial calcium flux and cytotoxicity. Excitation = 610nm; emission = 625nm. The iNeuMito™ biosensor is introduced into the cell using a proprietary magnetic liposome-mediated method and expressed in the mitochondria (using a marker protein such as COX IV).
iNeuATP™, a fluorescent biosensor, has also been custom incorporated into the human iNeuRapid™ cell line. With iNeuATP™, biosensor assays provide fast kinetics (resolution in seconds) when measuring real-time cellular ATP metabolism and cytotoxicity. The analysis of cellular oxidative phosphorylation directly reflects the health and function of mitochondria. Excitation = 535nm; emission = 550nm.
Starting Materials: immortalized human cell line.... Read More | Rabbit corneal epithelial cells (RbCEpC) are isolated from rabbit corneal epithelial tissue, which covers and protects the cornea from bacteria and other harmful organisms and substances. RbCEpC is cryopreserved in the X generation, and is cultivated and propagated at least when the X population hasRabbit corneal epithelial cells (RbCEpC) are isolated from rabbit corneal epithelial tissue, which covers and protects the cornea from bacteria and other harmful organisms and substances. RbCEpC is cryopreserved in the X generation, and is cultivated and propagated at least when the X population has doubled.... Read More |