Maldi TOF Mass Spectrometer (MALDI TOF MS)

MALDI TOF mass spectrometers (matrix-assisted laser desorption/ionization/time-of-flight) are amongst the most popular mass spec instruments in biology. They combine two technologies, the “soft” MALDI ionization source and the TOF mass analyzer. The latter measures an ion’s mass-to-charge ratio (m/z) by measuring the time it takes to reach a detector. The former volatilizes and ionizes those molecules using a laser, a target, and an organic compound called a matrix. In MALDI, a sample (for instance, a collection of tryptic peptides) is mixed with matrix, spotted and dried (crystallized) on the surface of a metal target plate. Upon irradiation with laser light, the matrix absorbs the energy and converts it to heat, which then causes the sample to ionize and explode off the plate into the mass analyzer. MALDI TOF mass spectrometers come in two basic flavors, MALDI TOF MS and MALDI TOF/TOF MS; the latter enables tandem MS (MS/MS) studies.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemAxima Assurance MALDI Time of Flight Mass SpectrometeriMScope QT Imaging Mass MicroscopeMALDI-8020 EasyCare Benchtop Linear MALDI-TOF Mass SpectrometerMALDImini-1 Compact MALDI Digital Ion Trap Mass SpectrometerMegaTOF Megadalton MALDI Mass Spectrometer
Citations
(5)
Catalog NumberAXIMA AssuranceiMScope QTMALDI-8020MALDImini-1MegaTOF
Price
Ionization Method(s)MALDIAtmospheric Pressure MALDI (AP-MALDI)MALDIMALDI ion sourceMALDI
Mass AnalyzerTOFQ-TOFTOFDigital Ion Trap (DIT)TOF
Resolution>5000 FWHMInquire> 5000 FWHM – ACTH 18-39 (m/z 2465)Inquire180 to 200 kDa
Scanning SpeedInquireInquireInquireInquire15 sec/position
Mass Range1 kDa to 500 kDaInquirem/z 1 - 500,000Inquire0.01 to 1.5 Mda
Description

An affordable, robust option for laboratories requiring routine manual or automated analysis of a wide variety of sample classes, the AXIMA Assurance provides high-quality, rapid MALDI mass spectra and an array of software tools for data processing and reporting. Incorporating a variable repetition

... Read More
InquireThrough innovative instrument design, the space-saving linear MALDI-8020 achieves performance specifications similar to those of larger, more expensive MALDI-TOF models but in a significantly smaller footprint. The MALDI-8020 improves laboratory efficiency and accelerates analysis through a newly ... Read MoreInquireThe MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.

Features
  • Ultrahigh sensitivity
  • Detects macromolecules up to 1,500,000 Da
... Read More
Get Quote