LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemOrbitrap Fusion™ Lumos™ Tribrid™ Mass SpectrometerOrbitrap Exploris™ 480 Mass SpectrometerQ Exactive™ UHMR Hybrid Quadrupole-Orbitrap™ Mass SpectrometerThermo Scientific™ Tox Explorer™ Collection for Orbitrap™ Exploris™ 120 MSTox Explorer™ Collection for Quantis™ Plus MS
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Catalog NumberIQLAAEGAAPFADBMBHQIQLAAEGAAPFARBMBKRIQLAAEGAAPFALGMAZRWFLOW-62002WFLOW-62003
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Ionization Method(s)HESIESI and HRAMInquireInquireInquire
Mass AnalyzerOrbitrapOrbitrapUHMR Hybrid Quadrupole-Orbitrap™InquireInquire
Scanning SpeedInquireUp to 40 Hz at resolution setting of 7500 at m/z 200up to 12 Hz at resolution setting of 12,500 at m/z 400Up to 22 HzInquire
Resolution7500-500,000 (FWHM) at m/z 200480,000 at m/z 195200,000 at m/z 400Up to 120,000 (FWHM) at m/z 200, demonstrates outstanding resolving power, according to a product pageInquire
DescriptionExcel at the most challenging of applications, including low level PTM analysis, multiplexed relative quantitation using isobaric tags, intact protein characterization, as well as MSn analysis of small molecules with the new Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer. This... Read MoreMaking genius simpler
Empowering life science researchers to translate each experimental step to a new level of insight with a next-generation ownership experience coupled with an intelligence-driven experimental approach. With the Thermo Scientific Orbitrap Exploris 480 mass spectrometer you'll
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The Thermo Scientific™ Q Exactive™ UHMR Hybrid Quadrupole-Orbitrap™ mass spectrometer is the first to provide the unique combination of unprecedented ultra-high mass range resolution, highest sensitivity, and MS2 and pseudo-MS3 capabilities needed to go beyond what’s possible with today’s native MS ... Read MoreAn all-in-one LC-MS/MS workflow solution for toxicology. HRAM option includes experimentally obtained compound database and HRAM spectral library with retention times of over 1800 compoundsAn all-in-one LC-MS/MS workflow solution for toxicology. Increase productivity with SRM acquisition speeds enabling faster polarity switching of both positive and negative compounds. Triple quadrupole option includes experimentally obtained compound database and retention times of over 1100 ... Read More
QuantityEAEAEAEAEA
TypeInquireOrbitrap LC-MSQuadrupole-Orbitrap LC-MSTox Explorer CollectionTox Explorer Collection
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