| Description | Discover the beauty of standardized and automated flow cytometry to make every cell count
The MACSQuant Analyzer 16 is an easy-to-use instrument for scalable and reliable flow cytometry assays. While the instrument supports a broad range of research applications, it is specifically designed to meetDiscover the beauty of standardized and automated flow cytometry to make every cell count
The MACSQuant Analyzer 16 is an easy-to-use instrument for scalable and reliable flow cytometry assays. While the instrument supports a broad range of research applications, it is specifically designed to meet the rigorous demands of cell and gene therapy (CGT) analytics. This is attributed to the following key features:
- Full workflow automation: From sample processing and compensation to acquisition and analysis, the instrument streamlines every step, ensuring consistent and reproducible results
- Seamless assay transfer: Achieve standardized, comparable results across multiple instruments and sites, enabling reliable data consistency and effortless scalability.
- Regulatory readiness: Featuring a dedicated software module for user management, electronic signatures, automatic analysis reports, and time-stamped audit trails, the MACSQuant Analyzer 16 ensures 21 CFR Part 11 compliance, streamlining data submission to regulatory authorities.
- Seamless integration into cell manufacturing workflows: Co-developed assays and harmonized software allow seamless integration into CliniMACS® Prodigy workflows, enhancing manufacturing efficiency through tailored in-process and release testing.
Together, these features make the MACSQuant Analyzer 16 an invaluable tool for CGT analytics while supporting and optimizing a wide range of other applications. Partner with us to standardize your flow cytometry workflows and meet the evolving demands of CGT development.... Read More | The MACSQuant® Tyto® Cell Sorter brings a gentler, safer, and sterile flow sorting technology to your lab. With the microchip technology at its heart, cells will no longer be exposed to electrical charge, decompression, and fluidic systems. Instead, cells are sorted within a single-use, The MACSQuant® Tyto® Cell Sorter brings a gentler, safer, and sterile flow sorting technology to your lab. With the microchip technology at its heart, cells will no longer be exposed to electrical charge, decompression, and fluidic systems. Instead, cells are sorted within a single-use, sterile, and closed cartridge, providing full safety for operators.
The MACSQuant Tyto is equipped with three lasers, which allows cell sorting with up to 10 parameters. The easy “plug and play” format of the instrument and the cartridge, combined with fully automated flow control, laser alignment, and valve timing, makes cell sorting accessible to any lab professional, without intensive training.
Features & benefits:
- Microchip technology enables gentler cell sorting
- Closed, single-use cartridge provides operator safety and prevents sample contamination
- Three lasers (405 nm, 488 nm, 638 nm), eight fluorescence channels, plus two scatter channels allow sorting with up to 10 parameters
Since the actual sorting process takes place completely within the Tyto Cartridge, there is no risk of losing precious sample material and therefore the sorting process is entirely operator-free. With its extremely compact design, the MACSQuant Tyto is a true benchtop instrument that perfectly fits into a typical lab environment.
The heart of the system is the MACSQuant Tyto Cartridge, a single-use disposable carrying the actual sorting microchip. Unlike in conventional droplet sorters, no fluidic tubing is present in the instrument itself. Additionally, cells sorted by the MACSQuant Tyto do not experience high sorting pressure, charge, or decompression. Instead, a very mild and constant filtered air pressure (< 3 psi) drives the cells through the microchip for sorting, and subsequently either into the positive or negative collection chamber (two-way sorting). The lack of fluidic tubing in the system means that fluidics start-up and laborious cleaning procedures are no longer required, saving operator-time and reducing costs. Furthermore, sorting temperature can be cooled down to 4 °C, providing optimal conditions to retain highest cell viabilities and functionalities.
Miltenyi Biotec offers three different cartridges to perfectly meet your experimental needs. The MACSQuant Tyto Cartridge is your choice to sort fragile cells with a flow rate of up to 55,000 cells/second and 30,000 valve actuations/second. The MACSQuant Tyto Cartridge HS has been specifically designed to facilitate never-before-seen high-speed cell sorting at a doubled flow rate (up to 110,000 cells/second). Furthermore, the MACS GMP Tyto Cartridge was specifically designed to facilitate the translation of multiparameter cell sorting protocols into clinics, including an extensive amount of documentation and regulatory support (CoA, CoO, and PIF).
The MACSQuant Tyto standard equipment includes an external 32-inch monitor for convenient data analysis. At the click of a button, you’ll have worldwide 24-hour remote support. Our live support service allows users to interact directly with MACSQuant Application Specialists in real time. Your dedicated support specialist can review your software setup and take control over the instrument to resolve any issues if desired.... Read More | "Discover the beauty of standardized and automated flow cytometry
The MACSQuant® Analyzer 10 brings to life the versatility and power required for modern flow cytometry applications. Whether mining for rare cells, analyzing the efficiency of your cell manufacturing process, or investigating "Discover the beauty of standardized and automated flow cytometry
The MACSQuant® Analyzer 10 brings to life the versatility and power required for modern flow cytometry applications. Whether mining for rare cells, analyzing the efficiency of your cell manufacturing process, or investigating signaling pathways, you are equipped for the task at hand.
Truly hands-free operation
With a range of automated features, the MACSQuant Analyzer 10 lays the foundation for true automation present in all instruments belonging to the MACSQuant Family of flow cytometers.
- Automated startup, cleaning, and shutdown
- Automated compensation
- Automated sample labeling
- Automated MACS® magnetic enrichment
- Automated calibration and quality control (QC)
Along with the MACSQuantify software complete automated assays are available:
- In-process and quality control in cellular therapy, i.e., chimeric antigen receptor (CAR) T cell manufacturing
- Toxicological assays
- Small particles/extracellular vesicle analysis
- 21 CFR Part 11 compliant option
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