New Column Formats for Faster and High Resolution Separations and Characterization of Monoclonal Antibody Variants

February 2011, Sunnyvale, CA—Dionex, the leader in monoclonal antibody (MAb) analysis solutions, is pleased to announce the release of three new MAbPac™ SCX-10 column formats for faster MAb analysis, pH gradients, and LC/MS use. The MAbPac SCX-10 is designed specifically for high-resolution analysis and characterization of MAb variants. The new formats include: 4 × 150 mm for fast MAb separations; 4 × 50 mm column for pH gradients; and 2 × 150 mm for upstream separations in LC/MS applications.

The MAbPac SCX-10 column’s unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants with high resolution. Hydrophobic interactions with the resin are essentially eliminated resulting in highly resolved peaks. The column, complementing the MAb Characterization platforms, is designed to address the regulatory requirements for biopharmaceutical characterization, providing unmatched column-to-column and lot-to-lot reproducibility.

For more information, visit www.dionex.com or contact your local Dionex representative.

Dionex (NASDAQ:DNEX) is a global leader in the manufacturing and marketing of liquid chromatography and sample preparation systems, consumables, and software for chemical analysis. The company’s systems are used worldwide in environmental analysis and by the life sciences, chemical, petrochemical, food and beverage, power generation, and electronics industries. Our expertise in applications and instrumentation helps analytical scientists to evaluate and develop pharmaceuticals, establish environmental regulations, and produce better industrial products.