Protein Aggregation Monitor (PAM ZERO)

The PAM ZERO is a simple-to-use tool to quickly measure and monitor protein aggregation, protein-protein interactions and kinetics, as needed in early stage drug discovery biochemistry labs.

From the box, connect the supplied USB cable to your PC and the power adaptor to the unit. Install the software and press “Start”! The intelligent software guides you through the process (except for your specific sample preparation needs).

You deal with the data exactly as specified in your lab protocols — we provide you the number and you save your data as per your proscribed methodologies.

The PAM ZERO provides the following benefits to you and your organization:

  • Reduced operating costs using a technician in lieu of analysts who can now concentrate on analysis & interpretation needs
  • Reduced footprint minimizes the use of your valuable & limited lab bench space
  • Reduced test sample preparation costs; only uses a small 2μl sample size
  • Consumes 0.0μl - none of your precious sample is consumed as the measurement is made in the pipette tip for further use!
  • No florescence tagging of your sample; it can be collected and reused with no affect
  • Shortened test turn around times by up to 90%; use it where samples are prepared and processed
  • Reduced capital costs for tight budgets
  • No internal PC to concern your IT group

PAM ZERO - 0.0μl Loss Protein Aggregation Monitor

  • 5 sec measurement, within a pipette tip, of aggregation & protein-protein interactions
  • Standard laser scattering combined with guided wave optics & microfluidics:
    • 90mm x 150mm x 20mm
    • 2μl min. sample volume
    • zero sample loss - retained in tip for additional tests
    • simple operation/no set-up
    • USB to Computer
  • Measures protein size - no fluorescent tagging to affect reaction kinetics & increase sample prep. time.
  • Software modular for ease of use in 3 measurement modes:
    • Static Aggregate Content
    • Reaction Kinetics
    • Protein MW
  • Technician friendly software:
    • Windows XP, Vista, 7
    • Fail safe algorithms flag up and reject poor data
    • Minimal user set up
    • Simple fixed report formats
    • Easy integration in 21 CFR Pt11 compliance systems

PAM permits a researcher to rapidly pre-screen samples at the lab. bench, reducing the numbers sent for costly testing by the central analytical facility. Turnaround can be reduced from weeks to days, saving valuable research dollars and pushing new therapies up the product pipeline faster

Norton Scientific Inc.
Thorold, ON Canada
+1 905-359-4445
[email protected].
www.norsci.ca

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