Platelet Aggregation Systems (Aggregometer)

Platelets are small cell fragments most commonly known for playing a role in wound repair and blood clotting via a clumping process known as platelet aggregation. Platelet aggregation systems (also referred to as an aggregometer) can be used to determine how well platelets stick together. Such a test measures platelet aggregation with the use of a platelet antagonist, such as ADP, thrombin, and ristocetin. An aggregometer measures the turbidity in the sample and records how quickly the platelets clump together by measuring the increased light and clarity in the sample. Additionally, a platelet aggregation system can encompass several test modes where the number of channels available in an aggregometer is equivalent to the number of tests that can be run simultaneously and independently. Certain aggregometers can test and measure platelet function from a patient and can be used to diagnose patients with von Willebrands disease. Platelet aggregation systems and aggregometers are reliable diagnostic tools in a clinical research laboratory.