Particle analyzers are used to determine the size and distribution of particles making up a material. Particle size analyzers are used in numerous fields for research and development, manufacturing and for quality control and product testing. Different technologies enable analysis across a wide range of sizes, of particles in powder, liquid, aerosol or other forms, and of materials ranging in diversity from soil, paint and cosmetics to nasal spray and proteins.
Laser diffraction particle size analyzers calculate particle size from the angle of light scattered by a stream of particles passing through a laser beam. This technique allows for continuous measurement of bulk material across a wide size range (10 nm to 3 mm). The size limits and sensitivity of a laser diffraction particle analyzer depend on the number and placement of detectors in the instrument. Dynamic light scattering particle analyzers are mainly used for analyzing particles in solution (size range: 1 nm to 6 um). Dynamic light scattering determines size from the fluctuations in scattered laser light intensity created by the particles’ Brownian motion. Induced grating particle size analyzers identify the size of even smaller particles (0.5 nm to 200 nm) in solutions by electrically aligning the particles and then measuring their diffusion.
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Malvern Panalytical
- 0.3 nm to 10 µm (diameter)2
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Entegris
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- Extinction, Scattering, Collimated, and/or Focused (sensor dependent)
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- Materials Testing, Pharmaceutical Lab
Malvern Panalytical
- 0.01 - 3500 µm
- Log-spaced array
- < 10 sec
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Shimadzu
- 7 nm to 800 µm
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Malvern Panalytical
- 0.3 nm to 10 µm (diameter)2
- Avalanche Photodiode
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Malvern Panalytical
- 0.1 to 2000 um
- 36 element log-spaced silicon diode detector array
- 30 s (Rapid mode), 60 min (Continuous mode)
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Shimadzu
- 17 nm to 2,500 µm
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Entegris
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- Focused beam, scatter 0.15-10+ µm at high concentration
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- Materials Testing, Pharmaceutical Lab
Brookhaven Instruments Corporation
- 0.01 to 30 µm maximum; 0.05 to 10 µm typical for low density particles, 0.01 to 2 µm for high density particles
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Entegris
- 0.5 – 400 µm
- Extinction, Scattering, Collimated, and/or Focused (sensor dependent)
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- Materials Testing, Pharmaceutical Lab
Entegris
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- 15 – 100 mW red laser diodes, 20 – 100 mW green laser diodes
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- Materials Testing, Pharmaceutical Lab
Entegris
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- Extinction, Scattering, Collimated, and/or Focused (sensor dependent)
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- Materials Testing, Pharmaceutical Lab
Entegris
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- Extinction, Scattering, Collimated, and/or Focused (sensor dependent)
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- Materials Testing, Pharmaceutical Lab
Entegris
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- Extinction, Scattering, Collimated, and/or Focused (sensor dependent)
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- Materials Testing, Pharmaceutical Lab
Entegris
- 0.3 nm– 10 µm
- 15 – 100 mW red laser diodes, 20 – 100 mW green laser diodes
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- Materials Testing, Pharmaceutical Lab
Entegris
- 0.15 to 400 µm
- Extinction and Scattering
- < 10s
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Entegris
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- PMT standard, optional 7X gain APD
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- Materials Testing, Pharmaceutical Lab
Brookhaven Instruments Corporation
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- Entrance aperture 3 mm, Coated, adjustable achromat for focusing scattered light onto 200 micron slit; slit position adjustable, Reflex mirrow and high quality eye piece for viewing scattering region through slit, Filter turret with 637, 532, 633, 514 and 488nm narrow band pass filters and 100, 200, and 400 micron, 1, 2, and 3 mm pinhole for SLS & DLS measurements.
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Brookhaven Instruments Corporation
- <0.6 nm to 10 um (at 173 degrees); 1 nm to 6 um (at 90 degrees)
- Avalanche Photodiode (APD)
- 1-2 minutes typical
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Microtrac Inc.
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- ~10 to 30 seconds
- Battery materials, chemicals, ceramics
Entegris
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- CMP slurries, other suspensions
Microtrac Inc.
- 30 µm to 5 mm (recommended 50 µm to 4.5 mm)
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- Battery materials, pigments, ceramics
Malvern Panalytical
- 0.1 - 1000 µm
- Log-spaced array
- < 10 sec
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Malvern Panalytical
- 0.1 - 1000 µm
- Log-spaced array
- < 10 sec
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Waters | Wyatt Technology
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- High-gain, high dynamic range, static light scattering detectors at 3 angles
- Depedent on LC separation
- With SEC/GPC: determination of distributions of absolute molar mass, size, conformation, conjugate ratio.
Microtrac Inc.
- 0.9 µm to 8 mm
0.9 µm to 8 mm (air pressure dispersion)
10 µm to 8 mm (gravity dispersion)
0.9 µm to 1 mm (wet dispersion) - Inquire
- ~ 1 to 3 min
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Microtrac Inc.
- recommended range 20 µm to 30 mm (with no hardware adjustment)
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- Chemicals, battery materials, ceramics
Bettersize Instruments Ltd.
- 0.3 nm to 15 µm
- Avalanche photodiode (APD)
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Microtrac Inc.
- F100 lens: 0.5 to 350 µm
F300lens: 1.4 to 1000 µm
F600 lens: 2.8 to 2000 µm - 32-element ring detector (with automatic optical axis adjustment function
- Spray measurement: 0.02 to 500 msec
Continuous measurement: 1 to 600 sec - Pigments, lotions, powders
Waters | Wyatt Technology
- 0.5 to 1000 nm
- Linearized avalanche photodiode for dynamic and static light scattering
- Measurement Time: 5 to 60 seconds per well
830 nm - Develop stable biopharmaceuticals, assess viral vector titer and aggregation, optimize protein buffers for crystallization, SAXS or chromatography, formulate theranostic nanoparticles, discover small-molecule and peptide inhibitors of protein-protein interactions
Malvern Panalytical
- 10 to 1000 nm
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- Extracellular Vesicles (EV), Virus and Vaccines, Drug Delivery & Gene Therapy, Biotherapeutics, Nanomaterials/colloids/toxicology, Ultrafine bubbles
Waters | Wyatt Technology
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- High-gain, high-dynamic range photodiodes at 3 detection angles for MALS. Optional avalanche photodiode for simultaneous dynamic light scattering measurements.
- Depedent on LC separation
- With SEC/GPC: determination of distributions of absolute molar mass, size, conformation, conjugate ratio. With Calypso CG-MALS: characterization of biomolecular interactions.
Bettersize Instruments Ltd.
- Wet dispersion: 0.02 to 2,600 µm
Dry dispersion: 0.1 to 2,600 µm
Dynamic imaging: 2.0 to 3,500 µm
- 92 detectors (forward, lateral and backward arrangements)
- Typical measurement time: Less than 10 seconds
- 3D Printing Materials, Abrasives, Batteries, Building Materials, Ceramics, Cosmetics, Food & Beverage, Mining & Materials, Paints, Inks & Coatings, Pharmaceuticals
Waters | Wyatt Technology
- Range from >1 µm (ECD) to <5 mm (ECD)
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- 1 minute/sample (BMI read time). 3 FL channels, 30 seconds/sample (FMM read time)
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Waters | Wyatt Technology
- Range from >1 µm (ECD) to <5 mm (ECD)
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- 1 minute/sample (BMI read time). 3 FL channels, 30 seconds/sample (FMM read time)
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Waters | Wyatt Technology
- Range from >1 µm (ECD) to <5 mm (ECD)
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- 1 minute/sample (BMI read time). 3 FL channels, 30 seconds/sample (FMM read time)
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Waters | Wyatt Technology
- >1 µm (ECD) to <5 mm (ECD)
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- 1 minute/sample (BMI read time). 3 FL channels, 30 seconds/sample (FMM read time)
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Malvern Panalytical
- 0.3 nm to 15 µm
- Avalanche Photodiode
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Waters | Wyatt Technology
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- High-gain, high-dynamic-range photodiodes at 18 angles for MALS; optional avalanche photodiode that may be placed at any of four angles for DLS.
Fluorescence-blocking filters available for use with analytes that fluoresce when illuminated at the MALS wavelength. - Depedent on LC separation
- With standard SEC/GPC or EclipseTM (FFF system): determination of distributions of molar mass, size, conformation, conjugation ratio and particle concentration.
With Calypso composition-gradient system: label-free characterization of biomolecular interactions including self- and hetero-association as well as non-specific interactions.
Beckman Coulter Life Sciences
- 10 nm to 3,500 µm
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- Very Advanced & Powerful Nanoparticle Size Analyzer
Malvern Panalytical
The NanoSight NS300 Nanoparticle Size and Concentration Analyzer is a very good tool for research work and I am completely satisfied with its results and efficiency. The cleaning of the sample chamber... Read Review - Versatile & Powerful Analyzer
Bettersize Instruments Ltd.
BeNano 180 Zeta Pro is an excellent device to measure the particle size, zeta potential, and molecular weight of our product samples. The device comes with excellent beam quality via a high-power ... Read Review - Top Particle Size Analyzer
Malvern Panalytical
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Waters | Wyatt Technology
The DAWN® MALS Instrument helps us to detect the molar mass, size, conformation, particle concentration, and conjugation in a solution. The device offers the highest grade of sensitivity & produces ... Read Review - Highly Functional Laser Particle Size Analyzer
Bettersize Instruments Ltd.
Bettersizer 2600 is a highly integrated analyzer that helps us in characterizng our raw materials with much ease and precision. It is a powerful analyzer that uses laser diffraction technology for ... Read Review - High Resolution & Accurate Nanoparticle Size and Concentration Analyzer
Malvern Panalytical
The NanoSight NS300 Nanoparticle Size and Concentration Analyzer is one of the best, high resolution, and very precise instruments. We are using this instrument for drug delivery systems and protein ... Read Review - Effective Particle Analyzer
Malvern Panalytical
We use this product to analyze different particles. It gives results very fast and it gives us all the informations that we need. It is a little difficult to use at first but once once you understand ... Read Review - Advanced Concentration Measurements
Malvern Panalytical
We use the Malvern Panalytical NS300 for nanoparticle characterization in solutions & are satisfied with its performance so far. The instrument is simple to set up & lets us conduct particle wise ... Read Review - Advanced & Excellent Particle Size Analyzer
Malvern Panalytical
The Zetasizer Ultra Particle Size Analyzer from Malvern Panalytical is one of the most advanced and easy to use. We are using this instrument to determine the size of molecules. Sometimes we are using... Read Review