Dynamic Light Scattering Particle Size Analysis (DLS)

Dynamic Light Scattering Particle Size Analysis (DLS) Dynamic light scattering particle size analyzers are used to measure the size of very small particles (0.6 nm to 6 um) in solution. This class of particle size analyzer interprets particles’ sizes from the fluctuations in scattered laser light created by the particles’ Brownian motion. Dynamic light scattering analysis is used in medical, biological research and materials science applications, and is also known as photon correlation spectroscopy or quasi-electron light scattering.

Although requiring suspension in a solution, particle size analysis by dynamic light scattering offers the advantage of measuring particles across a wide range of densities, from parts-per-million up to 40% of solution. Other advantages include size analysis of particles in their native environment and micro-liter scale minimum sample sizes. In addition, dynamic light scattering particle size analyzers may also provide information on particle shape and require less user training. Analysis times typically vary from 30 seconds to 2 minutes per sample.

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BeNano 180 Zeta Pro Nanoparticle Size and Zeta Potential Analyzer
Bettersize Instruments Ltd.
  • Particle Size:
    0.3nm - 15µm
  • Measuring Time:
    Inquire
  • Light Source:
    Inquire
BeNano 180 Zeta Pro Nanoparticle Size and Zeta Potential Analyzer
Bettersize Instruments Ltd.
  • Particle Size:
    0.3 nm - 15 um (DLS); 1 um - 50 um (Sedimentation)
  • Measuring Time:
    1-2 minutes (microrheology)
  • Light Source:
    50 mW Solid-state laser, 671 nm, Class 1
BI-200SM Research Goniometer and Laser Light Scattering System
Brookhaven Instruments Corporation
  • Particle Size:
    Inquire
  • Measuring Time:
    Inquire
  • Light Source:
    Inquire
Citations:
(321)
NanoBrook 90Plus
Brookhaven Instruments Corporation
  • Particle Size:
    1 nm to 6 um diameter
  • Measuring Time:
    1-2 minutes typical
  • Light Source:
    40 mW temperature-controlled semiconductor laser
NanoBrook Omni
Brookhaven Instruments Corporation
  • Particle Size:
    0.3 nm to 10 µm
  • Measuring Time:
    1-2 minutes typical
  • Light Source:
    40 mW red diode laser, 640 nm
NanoBrook Omni
Brookhaven Instruments Corporation
  • Particle Size:
    <0.6 nm to 10 um (at 173 degrees); 1 nm to 6 um (at 90 degrees)
  • Measuring Time:
    1-2 minutes typical
  • Light Source:
    40 mW red diode laser, nominal 640 nm wavelength
Citations:
(187)
Nanobrook Series Size And Zeta Potential Analyzers
Brookhaven Instruments Corporation
  • Particle Size:
    < 0.3 nm to 10 µm (DLS), 1 nm to 100 µm (Zeta)
  • Measuring Time:
    Inquire
  • Light Source:
    40 mW 640 nm temperature-controlled solid-state semiconductor laser. Alternative wavelengths available
NanoBrook ZetaPALS
Brookhaven Instruments Corporation
  • Particle Size:
    Inquire
  • Measuring Time:
    Seconds to minutes
  • Light Source:
    40 mW red diode laser, nominal 640 nm wavelength
Mini DLS System
Entegris
  • Particle Size:
    Inquire
  • Measuring Time:
    Inquire
  • Light Source:
    Inquire
Nicomp N3000
Entegris
  • Particle Size:
    0.3 nm to 10 µm
  • Measuring Time:
    ~2 minutes
  • Light Source:
    12 mW red laser diode (standard); optional 15, 35, 50, 100 mW red or 50, 100 mW green
Nicomp N3000 Nanoparticle Size Analyzer
Entegris
  • Particle Size:
    Inquire
  • Measuring Time:
    Inquire
  • Light Source:
    Inquire
Citations:
(1)
Nicomp N3000 Online System
Entegris
  • Particle Size:
    Inquire
  • Measuring Time:
    Inquire
  • Light Source:
    Inquire
Dual Light Nano Particle Sizer
Genizer LLC
  • Particle Size:
    1nm-10µm
  • Measuring Time:
    Fewer than 4 minutes
  • Light Source:
    Blue laser and green laser
nanoPartica SZ-100V2
HORIBA ABX Inc
  • Particle Size:
    0.3 nm to 10 µm
  • Measuring Time:
    Approximately 2 minutes
  • Light Source:
    Diode pumped frequency doubled laser, 532 nm (10 mW S2/Z2, 100 mW HS2/HZ2)
Zetasizer Lab
Malvern Panalytical
  • Particle Size:
    0.3 nm - 15 um
  • Measuring Time:
    Adaptive Correlation (automatic optimization)
  • Light Source:
    He-Ne laser 633 nm; 4 mW (Blue Label) / 10 mW (Red Label)
Zetasizer Pro
Malvern Panalytical
  • Particle Size:
    0.3 nm - 10 um
  • Measuring Time:
    Adaptive Correlation (automatic optimization)
  • Light Source:
    He-Ne laser 633 nm; 4 mW (Blue Label) / 10 mW (Red Label)
Zetasizer Pro Particle Size Analyzer
Malvern Panalytical
  • Particle Size:
    0.3 nm to 10 µm (diameter)2
  • Measuring Time:
    Inquire
  • Light Source:
    Inquire
Citations:
(70)
Zetasizer Ultra
Malvern Panalytical
  • Particle Size:
    0.3 nm - 15 um
  • Measuring Time:
    Adaptive Correlation (automatic optimization)
  • Light Source:
    He-Ne laser 633 nm; 4 mW (Blue Label) / 10 mW (Red Label)
NANOPHOX CS
Sympatec
  • Particle Size:
    0.5 nm - 10,000 nm
  • Measuring Time:
    < 1 - 3 min typical
  • Light Source:
    Laser
DynaPro Plate Reader 4 Dynamic Light Scattering Instrument
Waters | Wyatt Technology
  • Particle Size:
    0.5 to 1000 nm
  • Measuring Time:
    Measurement Time: 5 to 60 seconds per well
    830 nm
  • Light Source:
    830 nm, fiber-coupled diode laser
Citations:
(4)
DynaPro Plate Reader III
Waters | Wyatt Technology
  • Particle Size:
    0.5 to 1000 nm
  • Measuring Time:
    1 to 3600 seconds per well per read
  • Light Source:
    830 nm laser, programmable 10% to 100%
DynaPro ZetaStar
Waters | Wyatt Technology
  • Particle Size:
    0.2 to 1000 nm
  • Measuring Time:
    15 seconds typical
  • Light Source:
    785 nm laser, programmable 10% to 100%
DynaPro&trade; NanoStar&trade; II Dynamic Light Scattering Instrument
Waters | Wyatt Technology
  • Particle Size:
    0.2 to 1000 nm
  • Measuring Time:
    Inquire
  • Light Source:
    Inquire
NanoFlowSizer
InProcess-LSP
  • Particle Size:
    15 nm - 5000 nm (FIDES) / 3 nm - 5000 nm (THALIA)
  • Measuring Time:
    < 5 seconds per datapoint (real-time continuous)
  • Light Source:
    Laser (SR-DLS)
Inquire
Zetasizer Advance Ultra / Pro / Lab Particle Size Analyzer
Malvern Panalytical
  • Particle Size:
    0.3 nm to 10 µm
  • Measuring Time:
    Inquire
  • Light Source:
    Inquire
NANOTRAC FLEX
Microtrac
  • Particle Size:
    0.3 nm - 10 µm
  • Measuring Time:
    Fast measurement (real-time capable)
  • Light Source:
    780 nm laser diode, 3 mW
Inquire
NANOTRAC WAVE II
Microtrac
  • Particle Size:
    0.3 nm - 10 µm
  • Measuring Time:
    Fast measurement
  • Light Source:
    780 nm laser diode, 3 mW; 2 laser diodes with zeta
Inquire
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  • Bettersize Instruments Ltd.
  • Brookhaven Instruments Corporation
  • Entegris
  • Genizer LLC
  • HORIBA ABX Inc
  • InProcess-LSP
  • Malvern Panalytical
  • Microtrac
  • Sympatec
  • Waters | Wyatt Technology

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